In preclinical lung cancer models, researchers linked tumor production of the signaling molecule PGE2 to sensory nerves involved in cancer-associated wasting. A high-fat diet intended to increase calorie intake worsened illness under…
Read story: Cancer wasting may involve more than eating less: clues from animal models ↗Human datasets linked greater physical activity with a lower prevalence of some forms of clonal blood-cell production. In mice, uninterrupted sleep and…
Read story: Sleep and exercise may affect blood-cell clones differently by mutation ↗Researchers used a short computer task to study how people evaluate outcomes. Participants with major depression showed a higher and less flexible…
Read story: A brief game-like task offers clues about decision-making in depression ↗Across seven cohorts, higher blood p-tau217 was more strongly associated with subsequent cognitive impairment among APOE ε4 carriers. Follow-up analyses focused on…
Read story: Same blood marker, different risk links: genetics changes the picture ↗When mice received equal-calorie fructose or glucose, fructose suppressed hunger-related AgRP neuron activity less strongly. The research indicates that signals travelling from…
Read story: Fructose and glucose affect hunger circuits differently in mice ↗The ApexGO system used existing peptides as starting points to design modified candidates. Researchers synthesized and tested one hundred molecules in the…
Read story: AI helps researchers improve antibacterial peptide candidates ↗In a crossover trial involving 35 children with inattention and listening difficulties, remote microphone use improved speech understanding and auditory attention. Children…
Read story: Hearing the teacher more clearly may support classroom attention ↗Researchers assessed MiniDock in 1,380 people with suspected pulmonary tuberculosis across seven countries. Against culture-confirmed disease, sensitivity was 85.7% using sputum and…
Read story: A tongue swab instead of sputum for TB testing: findings from seven countries ↗Implanted electrodes translated brain signals into an avatar’s speech and upper-body movements. Three people with severe speech paralysis participated; simultaneous speech and…
Read story: Brain signals combine speech and gestures in a digital avatar ↗Fifteen people with peanut allergy received capsules containing gut microbes from non-allergic donors. After four months, tolerated peanut amounts increased in three…
Read story: Could gut microbes help with peanut allergy? An early small study ↗After quality control, researchers compared hippocampal tissue from 11 donors with a history of depression and 19 without. Depression was associated with…
Read story: Does nerve-cell development differ in depression? Clues from brain tissue ↗In experiments starting with 20-month-old female mice, semaglutide improved some movement and cognitive measures. With treatment continued until death, median lifespan was…
Read story: Semaglutide extended lifespan in older female mice: what does it mean for people? ↗Laboratory and animal models showed that abnormal tau changes could trigger reverse electron flow in mitochondria, which could further alter tau. An…
Read story: A new connection between tau protein and cellular energy production ↗Researchers followed 296 older adults who were cognitively normal at baseline. Among those with Alzheimer-related brain changes, more daily steps were associated…
Read story: Walking and brain health: benefits may not require 10,000 steps ↗Laboratory tests examined 39 sweeteners and 25 gut bacterial strains. Their effects could change in the presence of caffeine and certain medicines.
Read story: Sweeteners and gut bacteria may have a more complex relationship ↗Researchers studied two-way communication between brain circuits controlling sleep and growth hormone in mice.
Read story: The sleeping body stays busy: a sleep–hormone link in mice ↗A hydrocortisone-versus-placebo experiment analysed 26 participants to explore brain networks involved in emotional memory.
Read story: Why do some memories feel more vivid? ↗In the Cincinnati/Northern Kentucky region of the US, annual stroke incidence among adults aged 20–54 rose from 34 to 62 per 100,000…
Read story: Stroke is rising among younger adults—but where, and by how much? ↗
