After one cycling session in 25 healthy men, researchers found changes in more than 3,000 proteins across plasma, saliva and urine. A…
Read story: Thousands of proteins changed after one cycling session: a molecular map of exercise ↗Researchers tested human antibodies that bind alpha-gal in laboratory experiments. Some blocked allergic patients’ IgE from binding selected allergens; particular antibody formats…
Read story: Antibodies that block the immune response in meat allergy ↗Laboratory experiments found that antibiotic stress promoted protein transfer inside small bacterial vesicles. In E. coli, receiving these proteins increased persistence during…
Read story: Bacteria share proteins to survive antibiotic stress ↗Researchers examined eight familial melanoma genes in nearly 697,000 people across two datasets. Disease-associated variants exceeded a 2.5% prevalence threshold among people…
Read story: Genetic risk in melanoma: what age at diagnosis and multiple tumours reveal ↗The SenCat project compared more than 30 senescence conditions across 14 human cell types. RNA and protein measurements revealed no single marker…
Read story: No single signature identifies every senescent cell ↗Researchers examined 99 lymph-node sections from 51 donors aged 18–86, covering roughly 20 million cells. The location of senescence markers shifted with…
Read story: Mapping immune ageing: cell patterns shift in lymph nodes ↗Combining more than ten million cellular and spatial gene-expression profiles, researchers identified nine recurring tumour-neighbourhood patterns. Patterns recovered from blood cell-free DNA…
Read story: Can blood reveal the cellular neighbourhood around a tumour? ↗In preclinical lung cancer models, researchers linked tumor production of the signaling molecule PGE2 to sensory nerves involved in cancer-associated wasting. A…
Read story: Cancer wasting may involve more than eating less: clues from animal models ↗The ApexGO system used existing peptides as starting points to design modified candidates. Researchers synthesized and tested one hundred molecules in the…
Read story: AI helps researchers improve antibacterial peptide candidates ↗In experiments starting with 20-month-old female mice, semaglutide improved some movement and cognitive measures. With treatment continued until death, median lifespan was…
Read story: Semaglutide extended lifespan in older female mice: what does it mean for people? ↗
